ABSTRACT
Coronavirus disease 2019 (COVID-19) associated myocardial injury was caused by various mechanisms. We herein describe 2 cases presenting different types of myocardial injury due to Omicron variant. In both patients, diffuse reduced left ventricular (LV) wall motion in transthoracic echocardiography, electrocardiographic abnormality, and elevated myocardial enzymes were demonstrated. In addition, cardiovascular magnetic resonance (CMR) findings fulfilled the 2018 Lake Louise Criteria (LLC) for myocarditis. However, histological findings in 1 patient showed inflammatory cell infiltration with myocyte degeneration, while those in the other showed interstitial edema without inflammatory cell infiltration. Histological findings were crucial for a differential diagnosis of myocardial injury due to Omicron variant.
Subject(s)
COVID-19 , Heart Injuries , Myocarditis , Humans , SARS-CoV-2 , COVID-19/complications , Myocarditis/diagnosis , Myocarditis/etiology , Myocardium/pathologySubject(s)
BNT162 Vaccine/adverse effects , COVID-19/complications , Myocarditis/diagnosis , Adverse Drug Reaction Reporting Systems , Aspirin/administration & dosage , Aspirin/therapeutic use , BNT162 Vaccine/administration & dosage , C-Reactive Protein , Diuretics/administration & dosage , Diuretics/therapeutic use , Humans , Male , Middle Aged , Myocarditis/chemically induced , Myocarditis/drug therapy , Natriuretic Peptide, Brain/blood , RNA, Messenger , SARS-CoV-2 , Vaccination/adverse effectsABSTRACT
BACKGROUND: The prevalence of deep venous thrombosis (DVT) among hospitalized psychiatric patients after coronavirus disease 2019 (COVID-19) infection remains unclear.MethodsâandâResults:We retrospectively investigated the prevalence of proximal DVT after COVID-19 infection among 50 hospitalized patients in a Japanese psychiatric hospital that in which a COVID-19 cluster developed between August and September 2020. The prevalence of proximal DVT was 10.0%. Patients with proximal DVT had a lower body weight and higher maximum D-dimer levels and International Medical Prevention Registry on Venous Thromboembolism (IMPROVE) VTE scores. CONCLUSIONS: After COVID-19 infection, hospitalized psychiatric patients are at high risk of DVT and should be carefully followed up.